June 20, 2019
Synergism between myosin II contractility and cofilin activity modulates serotonin-dependent axon growth. Normally, cofilin-dependent decreases in actin density are compensated by increases in point contact density and traction force; however, myosin hyperactivation leads to catastrophic decreases in actin network density and neurite retraction.
For the full article, visit: http://jcb.rupress.org/content/early/2019/05/22/jcb.201810054